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Genomic Profiling and Translational Research: Study Designs, Analyses and Applications
March 4, 2014 @ 4:00 pm - 6:00 pm
The Center for Genetic Medicine of Northwestern University welcomes you to attend the Richard A. Scott, MD Lecture, featuring Nicholas J. Schork, PhD, Professor and Director of Human Biology at the J. Craig Venter Institute (JCVI) and adjunct Professor of Psychiatry and Family and Preventive Medicine (Division of Biostatistics) at the University of California, San Diego (UCSD).
Technological advances in genetic and molecular assays have provided an unprecedented ability to identify and characterize the potentially unique determinants of an individual’s disease. However, the routine use of ‘individualized,’ ‘personalized’ or ‘precision’ medicine in clinical settings will be hampered until the technologies are appropriately vetted. Dr. Schork will describe studies that use genomic profiling to further translational research, focusing on the formidable issues of patient genetic background heterogeneity, matching drugs to tumor genomic profiles in real-time clinical trial settings, and the utility of ‘personalized’ therapeutic interventions. These studies illustrate the ability of precision medicine initiatives to have positive impacts on health care, but only after some of the accompanying challenges have been exposed and dealt with appropriately.