If You’re on Medication, Beware of the Grapefruit Effect

What do the drugs Percocet, Lipitor, and Wellbutrin have in common? It’s not what they do for you – one’s a pain med, another treats heart disease, and the third helps with depression. They’re not made by the same drug company, nor are they regulated the same way by the government. These drugs couldn’t be more different in the way they work, why they work, and how they’ve impacted our healthcare system. So what is it that they all have in common?

They, like many other drugs, can turn on you and cause you harm if you take them with grapefruit juice.

This is called the grapefruit effect.

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The Discovery of Vaccines: Then and Now

In the doctor’s office, a little toddler smiles joyfully as the doctor releases the plunger and withdraws the syringe from his arm. This was the first of a series of shots that he was scheduled to receive as part of his vaccination regimen. The doctor applies a bandage to the toddler’s arm, adds the vaccination to his records, and asks the family if they had any questions before leaving for the day.  

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The Strange History of Antidepressants

Ironically, despite the horrors of war, armed conflict has a way of advancing medicine. Gruesome injuries sustained on the battlefield provide opportunities for surgeons to experiment and test new approaches for treatment. During World War II for example, blood poisoning, bronchitis, and other infectious diseases contracted by soldiers created a demand for broad spectrum antibiotics, which encouraged British scientists to find new ways to produce penicillin on a mass scale.

Sometimes, weapons of war themselves have applications other than mass destruction. Consider hydrazine (N2H4), a chemical compound that received renewed recognition by the military-industrial complex in 1937 Germany. Continue reading “The Strange History of Antidepressants”